The Madame Web cast features Dakota Johnson, Sydney Sweeney and Isabela Merced. This info article contains minor spoilers and cast/character summaries for S.J. Clarkson’s 2024 movie on Netflix. Check out more streaming guides in Vague Visages’ Know the Cast category, and then browse complete soundtrack song listings in the Soundtracks of Cinema section.

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Madame Web takes place in 2003. After a near-death experience, a female paramedic sees visions of the future. The narrative follows the main protagonist as she strategizes a mutant explorer with three feisty teenagers. Here’s every actor and character in Madame Web, the fourth film in Sony’s Spider-Man Universe.

Read More at VV — Know the Cast: ‘Unfrosted’

Madame Web Cast: Dakota Johnson as Cassandra Web

Character Profile: An FDNY paramedic. She thinks about her later mother while experiencing déjà vu. Cassandra protects three teenage girls from a scheming explorer.

Johnson’s Resume: Amelia Ritter in The Social Network (2010), Anastasia Steele in The Fifty Shades of Grey Movie Franchise (2015-2018), Susie in Suspiria (2018), Maggie Sherwoode in The High Note (2020), Nina in The Lost Daughter (2021)

Read More at VV — Know the Cast: ‘Miller’s Girl’

Madame Web Cast: Sydney Sweeney as Julia Cornwall

Character Profile: A New York City teenager. She lives with her father as her mother spends time in a psych ward. Julia uses Taekwondo while strategizing against a mutant explorer.

Sweeney’s Resume: Eden Spencer in The Handmaid’s Tale (2018), Alice in Sharp Objects (2018), Cassie Howard in Euphoria (2019-), Snake in Once Upon a Time in Hollywood (2019), Olivia Mossbacher in The White Lotus (2021)

Read More at VV — Know the Cast: ‘Rust Creek’

Madame Web Cast: Isabela Merced as Anya Corazón

Character Profile: Cassandra’s neighbor. She worries about a possible deportation or living in a foster system. Anya vows to law low until her 18th birthday.

Merced’s Resume: Isabel Reyes in Sicario: Day of the Soldado (2018), Lizzy in Instant Family (2018), Dora in Dora and the Lost City of Gold (2019), Rachel Cooper in Sweet Girl (2021), Aza Holmes in Turtles All the Way Down (2024)

Read More at VV — Know the Cast: ‘Scoop’

Madame Web Cast: Celeste O’Connor as Mattie Franklin

Character Profile: A New York City teenager. She is a skateboarder with rich parents. Mattie lives alone with a housekeeper.

O’Connor’s Resume: Amy in Wetlands (2017), Teen Abbie in Irreplaceable You (2018), Nyla Chones in Freaky (2020), Lucky in Ghostbusters: Afterlife (2021), Ryan in A Good Person (2023)

Read More at VV — Know the Cast: ‘The Tearsmith’

Madame Web Cast: Tahar Rahim as Ezekiel Sims

Character Profile: A mutant explorer who can see the future. He acquires supernatural skills after stealing a spider in 1973 Peru. Ezekiel tries to prevent Julia, Anya and Mattie from killing him.

Rahim’s Resume: Malik El Djebena in A Prophet (2009), Prince Auda in Day of the Falcon (2011), Samir in The Past (2013), Mohamedou Ould Slahi in The Mauritanian (2021), Paul Barras in Napoleon (2023)

Read More at VV — Know the Cast: ‘Irish Wish’

The Madame Web cast also includes:

• Mike Epps as O’Neil
• Emma Roberts as Mary Parker
• Adam Scott as Ben Parker
• Kerry Bishé as Constance
• Zosia Mamet as Amaria
• José María Yazpik as Santiago
• Kathy-Ann Hart as Susan
• Josh Drennen as Julia’s Dad
• Yuma Feldman as Julia’s Half-Sibling
• Miranda Adekoje as Doctor (Optometry)

Q.V. Hough (@QVHough) is Vague Visages’ founding editor.