The Locked In cast features Famke Janssen, Rose Williams and Alex Hassell. This info article contains minor spoilers and character details for Nour Wazzi’s 2023 Netflix movie. Check out more streaming guides in Vague Visages’ Know the Cast section.

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Locked In explores the relationship between a famous actress and her adopted daughter. When Katherine wakes up in a hospital, a nurse diagnoses her with locked-in syndrome. The narrative examines the events that preceded a vicious attack. Here’s every main actor and character in Locked In.

Read More at VV — Know the Cast: ‘The Killer’

Locked In Cast: Famke Janssen as Katherine

Character Profile: A famous actress. She tries to communicate with a nurse after being attacked. Katherine is a vindictive woman who resents her adoptive daughter.

Janssen’s Resume: Xenia Onatopp in Goldeneye (1995), Evelyn in House on Haunted Hill (1999), Jean Grey in X-Men (2000), Lenore in Taken (2008), Olivia Godfrey in Hemlock Grove (2013-15)

Read More at VV — Know the Cast: ‘Best. Christmas. Ever!’

Locked In Cast: Rose Williams as Lina

Character Profile: Katherine’s adoptive daughter and daughter-in-law. She journals about violent fantasies. Lina marries Katherine’s step-son.

Williams’ Resume: Claude de Valois in Reign (2014-17), Young Vinnie in A Quiet Passion (2016), Charlotte Heywood in Sanditon (2019-), Faith Palladino in Curfew (2019), Pamela Penrose in Mrs. Harris Goes to Paris (2022)

Read More at VV — Know the Cast: ‘Nyad’

Locked In Cast: Alex Hassell as Doctor Lawrence

Character Profile: Katherine’s regular doctor. He is a close family friend with secrets to protect. Doctor Lawrence develops a romantic relationship with Lina while over-prescribing painkillers to her husband.

Hassell’s Resume: Louis in Suburbicon (2017), Translucent in The Boys (2019), Ross in The Tragedy of Macbeth (2021), Jason in Violent Night (2022), Rick in Everything Now (2023)

Read More at VV — Know the Cast: ‘Wingwomen’

Locked In Cast: Finn Cole as Jamie

Character Profile: Katherine’s step-son and Lina’s husband. He suffers from seizures. Jamie gets caught up in a murder conspiracy.

Cole’s Resume: Michael Gray in Peaky Blinders (2014-22), Joshua “J” Cody in Animal Kingdom (2016-22), Don Wallace in Slaughterhouse Rulez (2018), Eugene Evans in Dreamland (2019), Young Jakob in F9: The Fast Saga (2021)

Read More at VV — Know the Cast: ‘Sister Death’

Locked In Cast: Anna Friel as Nurse Mackenzie

Character Profile: Jamie’s nurse. She is a neurochemical specialist who treats Katherine. Nurse Mackenzie clashes with Doctor Lawrence.

Friel’s Resume: Lady Claire in Timeline (2003), Roz Harmison in Goal! The Dream Begins (2005), Charlotte “Chuck” Charles in Pushing Daisies (2007-09), Holly Cantrell in Land of the Lost (2009), Marcella Backland/Keira May Devlin in Marcella (2016-20)

Read More at VV — Know the Cast: ‘Pain Hustlers’

The Locked In cast also includes:

• Georgia Thorne as Young Lina
• Toby Ryan as Young Jamie
• Karl Collins as Neurosurgeon
• Lesley Molony as Doctor
• Chris Hallaways as First Arborist
• Cameron Robertson as Landlord
• Hope Delaney as Katherine’s TV Daughter

Q.V. Hough (@QVHough) is Vague Visages’ founding editor.