The Pulse cast features Willa Fitzgerald as Danielle Simms, Colin Woodell as Xander Phillips and Jessie T. Usher as Sam Elijah. This info article contains minor spoilers and character details for Zoe Robyn’s Netflix series. Check out more cast guides in Vague Visages’ Know the Cast category.

Pulse takes place at Maguire Hospital in Miami, Florida. When Danielle “Danny” Simms becomes the new chief resident, she worries about an internal investigation involving her colleague and lover. The narrative follows the main protagonists as they resolve personal and professional issues during a hurricane. Here’s every actor and character in Pulse.

Read More at VV — Know the Cast: ‘Adolescence’

Pulse Cast: Willa Fitzgerald as Danielle Simms

Character Profile: The new chief resident of emergence medicine at Maguire Hospital. She is a Homestead, Florida native who lacks confidence. Danielle clashes with trusted colleagues while starting a new position.

Fitzgerald’s Resume: Emma Duval in Scream: The TV Series (2015-16), Meg March in Little Women (2017), Colette French in Dare Me (2019-20), Roscoe Conklin in Reacher (2022), Young Madeline in The Fall of the House of Usher (2023)

Read More at VV — Know the Cast: ‘Caught’

Pulse Cast: Colin Woodell as Xander Phillips

Character Profile: Danielle’s mysterious love interest. He is a privileged man from a wealthy family who loses a chief resident position due to an internal investigation. Xander protects a secret about the past involving a patient’s death.

Woodell’s Resume: Aiden in The Originals (2014-18), Buckley Ware/Feliks in The Flight Attendant (2020-22), EMT Scott in Ambulance (2022), Winston Scott in The Continental (2023), Buzz Aldrin in Fly Me to the Moon (2024)

Read More at VV — Know the Cast: ‘The Residence’

Pulse Cast: Jessie T. Usher as Sam Elijah

Character Profile: Danielle’s colleague and trusted friend. He gets disappointed after not being promoted to chief resident. Sam adores Danielle but tries not to make her feel uncomfortable.

Usher’s Resume: Cam Calloway in Survivor’s Remorse (2014-17), Dylan Hiller in Independence Day: Resurgence (2016), A-Train/Reggie Franklin in The Boys (2019-), Davon in Tales of the Walking Dead (2022), Trevor in Smile (2022)

Read More at VV — Know the Cast: ‘Zero Day’

Pulse Cast: Justina Machado as Natalie Cruz

Character Profile: The chair of surgery and emergency medicine at Maguire Hospital. She keeps a close eye on students. Natalie tries to repair her professional relationship with Danielle.

Machado’s Resume: Vanessa Diaz in Six Feet Under (2001-05), Isabella Hudson in Final Destination 2 (2003), Henderson in Torque (2004), Darci Factor in Jane the Virigin (2016-19), Penelope Alvarez in One Day at a Time (2017-20)

Read More at VV — Know the Cast: ‘Running Point’

Pulse Cast: Jack Bannon as Tom Cole

Character Profile: A surgical resident with a bad reputation. He is a graduate of Rutgers University and John Hopkins University. Tom finds trouble in the workplace due to his flirtatious personality.

Bannon’s Resume: Sam Thursday in Endeavour (2013-23), Christopher Morcom in The Imitation Game (2014), Angelo Poliziano in Medici (2018-19), Alfred Pennyworth in Pennyworth (2019-22), Lukas in The Darkness (2024)

Read More at VV — Know the Cast: ‘Apple Cider Vinegar’

Pulse Cast: Daniela Nieves as Camila Perez

Character Profile: A third-year medical student. She is a Grey’s Anatomy fan who bonds with an intern. Camila lightly clashes with colleagues but tries to understand their point of view.

Nieves’ Resume: Adriana Montiel in El Rostro de Analía (2008-09), Andi Cruz in Every Witch Way (2014-15), Grace in Save Me (2020), Lissa Dragomir in Vampire Academy (2022), Lyssa in Sex Appeal (2022)

Read More at VV — Know the Cast: ‘Black Doves’

Pulse Cast: Chelsea Muirhead as Sophie Chan

Character Profile: A surgical intern. She is a former beauty queen from Churobusco, Indiana. Sophie clashes with Camila and ultimately develops romantic feelings for her.

Muirhead’s Resume: Gossip Girl #1 in Impulse (2019), Sasha in Slow Pitch (2020-22), Yan Mi in Warrior (2023), Rachel Flowers in Law & Order Toronto: Criminal Intent (2024), Megan in A Chef’s Deadly Revenge (2024)

Read More at VV — Know the Cast: ‘The Madness’

Pulse Cast: Jessy Yates as Harper Simms

Character Profile: Danielle’s sister. She is a Harvard graduate and a second-year emergency medicine student. Harper became paralyzed due to a childhood incident involving her father.

Yates’ Resume: Nora in Speechless (2017), Alicia Ford in Law & Order: Special Victims Unit (2021), Morgan in Me (2024), Rae in Skillsville (2025)

Read More at VV — Know the Cast: ‘A Man on the Inside’

The Pulse cast also includes:

• Arturo Del Puerto as Luis Dominguez
• Santiago Segura as Gabriel Moreno
• Nestor Carbonell as Dr. Ruben Soriano
• Jessica Rothe as Cass Himmelstein
• Ash Santos as Nia Washington
• Sophia Torres as Vero Cruz
• Brenda Arteaga-Walsh as Ines
• Kathryn Smith-McGlynn as Shannon Kincaid
• Michael William Freeman as Glenn Vogel
• J.R. Ramirez as Dr. Patrick Sanchez
• Evan Bittencourt as Miguel
• Mimi Fletcher as Janette
• Ramona DuBarry as Loretta Washington
• Victor Cordova as Nico Villarreal

Q.V. Hough (@QVHough) is Vague Visages’ founding editor.