The Lessons in Chemistry cast features Brie Larson, Lewis Pullman and Aja Naomi King. This info article contains minor spoilers and cast/character summaries for Lee Eisenberg’s Apple TV+ series. Check out more streaming guides in Vague Visages’ Know the Cast category, and then browse complete soundtrack song listings in the Soundtracks of Cinema section.

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Lessons in Chemistry centers on an American chemist. In the 1950s, Elizabeth Zott meets a temperamental doctor while working as a lab technician. The narrative follows the main protagonists as they build a romantic relationship while developing their careers. Here’s every actor and character in Lessons in Chemistry, an adaptation of Bonnie Garmus’ 2022 novel.

Read More at VV — Know the Cast: ‘Flora and Son’

Lessons in Chemistry Cast: Brie Larson as Elizabeth Zott

Character Profile: An American chemist. She experiences misogyny during the 1950s after graduating from the top of her class at UCLA. Elizabeth transforms into a TV personality.

Larson’s Resume: Kate Gregson in United States of Tara (2009-11), Grace in Short Term 12 (2013), Ma in Room (2015), Mason Weaver in Kong: Skull Island (2017), Carol Danvers in the MCU (2019-)

Read More at VV — Know the Cast & Characters: ‘The Morning Show’

Lessons in Chemistry Cast: Lewis Pullman as Calvin Evans

Character Profile: A doctor with a jazz mindset. He is a famous chemist who feels pressure to secure a grant. Calvin exercises to calm his mind.

Pullman’s Resume: Dallas in Lean on Pete (2017), Miles Miller in Bad Times at the El Royale (2018), Garret in Them That Follow (2019), Major Major in Catch-22 (2019), Bob in Top Gun: Maverick (2022)

Read More at VV — Know the Cast: ‘The Changeling’

Lessons in Chemistry Cast: Aja Naomi King as Harriet Slone

Character Profile: Calvin’s neighbor. She is a legal aid with two kids and a husband in Korea. Harriet rallies for equality while trying to maintain her reputation.

King’s Resume: Dr. Cassandra Kopelson in Emily Owens M.D. (2012–13), Abigayle in Four (2012), Michaela Pratt in How to Get Away with Murder (2014-20), Cherry in The Birth of a Nation (2016), Latrice in The Upside (2017)

Read More at VV — Know the Cast & Characters: ‘Foundation’

The Lessons in Chemistry cast also includes:

• Stephanie Koenig as Fran Frask
• Alice Halsey as Madeline Evans Zott
• Joshua Hoover as Anthony
• Yasir Hashim Lafond as James “Junior” Sloane
• Brandon Gibson as Tom Clemens
• Joy Jacobson as Shari
• Shoo Shoo Parsells as Amanda Pine
• Hero Hunter as Junior Sloane – 10yrs
• Patrick Walker as Wakely
• Derek Cecil as Dr. Robert Donatti
• Thomas Mann as Boryweitz
• Andy Daly as Dr. Price
• Robert Alan Beuth as Frank Marsten
• Debbie Pollack as Louise
• Ali Kinkade as Jenny Marie Kay

Q.V. Hough (@QVHough) is Vague Visages’ founding editor.