The Anaconda cast features Jack Black, Paul Rudd and Steve Zahn. This info article contains minor spoilers and character details for Tom Gormican’s 2025 movie on Amazon and Netflix. Check out more cast guides in Vague Visages’ Know the Cast category.

Anaconda centers on an American cinephile and his best friend. When Doug learns about an opportunity to remake the 1997 thriller Anaconda, he travels to Brazil to produce a low-budget movie with his inner circle of friends. The narrative follows the main protagonist as he encounters various obstacles while receiving emotional support from his wife and collaborators. Here’s every actor and character in Anaconda, the seventh installment of the movie franchise.

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Anaconda Cast: Jack Black as Doug McCallister

Character Profile: A wedding videographer. He travels to the Amazon rainforest to produce a remake of the 1997 film Anaconda. Doug doesn’t know that a trusted collaborator didn’t actually acquire the rights for the source material.

Black’s Resume: The Lead Singer of Tenacious D — Also, Barry Judd in High Fidelity (2000), Dewey Finn in School of Rock (2003), Po in the Kung Fu Panda Movie Franchise (2008-), Carl Denham in the King Kong Franchise (2005-)

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Anaconda Cast: Paul Rudd as Ronald Griffin Jr.

Character Profile: Doug’s best friend. He is a pretentious background actor. Ronald lies about acquiring the rights to remake Anaconda.

Rudd’s Resume: Josh in Clueless (1995), Brian Fantana in Anchorman: The Legend of Ron Burgundy (2004), David in The 40-Year-Old Virgin (2005), Pete in Knocked Up (2007), Scott Lang/Ant-Man in the MCU (2015-)

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Anaconda Cast: Steve Zahn as Kenny Trent

Character Profile: Doug and Ronald’s friend. He is a recovering alcoholic and fellow crew member. Kenny overcomes a psychological obstacle while trying to urinate in the Amazon rainforest.

Zahn’s Resume: Wayne in Saving Silverman (2001), Al Giordino in Sahara (2005), Duane in Rescue Dawn (2006), Bad Ape in War for the Planet of the Apes (2017), Mark Mossbacher in The White Lotus (2021)

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Anaconda Cast: Thandiwe Newton as Claire Simons

Character Profile: Doug’s friend and Ronald’s former flame. She earns an acting role in the Anaconda remake. Claire strategizes against a surprise enemy in Brazil.

Newton’s Resume: Cookie in Gridlock’d (1997), Nyah Hall in Mission: Impossible II (2000), Christine in Crash (2004), Maeve Millay in Westworld (2016-), Celia Harrison in All the Old Knives (2022)

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Anaconda Cast: Daniela Melchior as Ana Almeida

Character Profile: The alleged daughter of a Brazilian boat operator. She is actually an underground gold miner. Ana manipulates Doug and his crew members.

Melchior’s Resume: Isabel Vasconcellos in Valor da Vida (2018-19), Ratcatcher 2 in The Suicide Squad (2021), Ura in Guardians of the Galaxy Vol. 3 (2023), Isabel in Fast X (2023), Ellie in Road House (2024)

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Anaconda Cast: Selton Mello as Santiago

Character Profile: A snake handler. He works as an advisor for Doug and Ronald’s Anaconda remake. Santiago struggles emotionally after the violent death of his beloved snake.

Mello’s Resume: Lourenço in O Cheiro do Ralo (2006), Benjamim/Pangaré in The Clown (2011), Lino in Lino (2017), Caio Barone in Sessão de Terapia (2019-21), Rubens Paiva in I’m Still Here (2024)

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The Anaconda cast also includes:

• Ice Cube as Himself
• Ione Skye as Malie
• Rui Ricardo Diaz as Joao
• John Billingsley as Jerry
• Sebastian Sero as Charlie
• Diego Arnary as Paulo
• Dan Silveira as Timo
• Ana Francesca Armenia as Bride
• Jarred Blakiston as Groom

Q.V. Hough (@QVHough) is Vague Visages’ founding editor.