The Mission: Impossible II cast features Tom Cruise, Dougray Scott and Thandie Newton. This info article contains minor spoilers and character details for John Woo’s 2000 movie on Paramount+ and Starz. Check out more cast guides in Vague Visages’ Know the Cast category.

Mission: Impossible II centers on a government spy named Ethan Hunt. When a rogue IMF agent steals the cure for a virus, he intends to profit from a pandemic. The narrative follows Ethan as he teams up with his crew and a professional thief. Here’s every actor and character in Mission: Impossible II, the second installment of the movie franchise.

Read More at VV — Know the Cast: ‘Mission: Impossible’

Mission: Impossible II Cast: Tom Cruise as Ethan Hunt

Character Profile: An IMF agent. He gets assigned to recover the cure for a chimeric virus. Ethan tracks down a rogue IMF agent.

Cruise’s Resume: Ron Kovic in Born on the Fourth of July (1989), Ethan Hunt in the Mission: Impossible Movie Franchise (1996-), Jerry Maguire in Jerry Maguire (1996), Frank T.J. Mackey in Magnolia (1999), Nathan Algren in The Last Samurai (2003)

Read More at VV — Know the Cast: ‘The Bourne Identity’

Mission: Impossible II Cast: Dougray Scott as Sean Ambrose

Character Profile: An IMF agent. He steals the cure for a chimeric virus. Ambrose wants to start a pandemic.

Scott’s Resume: Prince Henry in Ever After: A Cinderella Story (1998), Mike Whittier in Hitman (2007), Arthur Miller in My Week with Marilyn (2011), Colonel Jacob Kane in Batwoman (2019-22), Erik Kynch in Exterritorial (2025)

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Mission: Impossible II Cast: Thandie Newton as Nyah Hall

Character Profile: Ambrose’s ex-girlfriend. She is a professional thief who gets recruited by the IMF. Nyah injects herself with a virus.

Newton’s Resume: Cookie in Gridlock’d (1997), Christine in Crash (2004), Dame Vaako in The Chronicles of Riddick (2004), Linda in The Pursuit of Happyness (2006), Maeve Millay in Westworld (2016-22)

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Mission: Impossible II Cast: Ving Rhames as Luther Strickell

Character Profile: An IMF agent. He is a tech expert who assists Ethan during a mission. Luther helps save Nyah’s life.

Rhames’ Resume: Marsellus Wallace in Pulp Fiction (1994), Luther in the Mission: Impossible Franchise (1996-), Nathan “Diamond Dog” Jones in Con Air (1997), Marcus in Bringing Out the Dead (1999), Charlie-27 in Guardians of the Galaxy Vol. 2 (2017)

Read More at VV — Know the Cast: ’28 Days Later’

Mission: Impossible II Cast: Richard Roxburgh as Hugh Stamp

Character Profile: Ambrose’s associate. He participates in a pandemic scheme. Hugh seemingly kills Ethan during a fateful encounter.

Roxburgh’s Resume: The Duke in Moulin Rouge! (2001), Count Vladislaus Dracula in Van Helsing (2004), Cleaver Greene in Rake (2010-18), Frank in Sanctum (2011), Vernon in Elvis (2022)

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The Mission: Impossible II cast also includes:

• John Polson as Billy Baird
• Brendan Gleeson as McCloy
• Rade Serbedzija as Dr. Nekhorvich
• William Mapother as Wallis
• Dominic Purcell as Ulrich
• Matthew Wilkinson as Michael
• Nicholas Bell as McCloy’s Accountant
• Cristina Brogeras as Flamenco Dancer #4
• Ken Chan as McCloy’s Chemist
• Kim Fleming as Larrabee

Q.V. Hough (@QVHough) is Vague Visages’ founding editor.