The Fountain of Youth cast features John Krasinski, Natalie Portman and Eiza González. This info article contains minor spoilers and character details for Guy Ritchie’s 2025 Apple TV+ movie. Check out more cast guides in Vague Visages’ Know the Cast category.

Fountain of Youth explores the professional relationship between a male archaeologist and his museum curator sister. As Luke and Charlotte Purdue track down a mythical location, they receive assistance from a seemingly sick colleague. The narrative follows the main protagonists as they attempt to survive a fantastic voyage. Here’s every actor and character in Fountain of Youth.

Read More at VV — Know the Cast: ‘The Gorge’

Fountain of Youth Cast: John Krasinski as Luke Purdue

Character Profile: An archaeologist. He recruits his sister for a huge mission. Luke strategizes against an underground organization while trying to locate the Fountain of Youth.

Krasinski’s Resume: Jim Halpert in The Office (2005-13), Jack Silva in 13 Hours: The Secret Soldiers of Benghazi (2016), Jack Ryan in Tom Clancy’s Jack Ryan (2018-23), Lee Abbott in A Quiet Place (2018), Dad/Marshmellow in IF (2024)

Read More at VV — Know the Cast: ‘Fancy Dance’

Fountain of Youth Cast: Natalie Portman as Charlotte Purdue

Character Profile: Luke’s sister. She is a museum curator in England. Charlotte reluctantly joins Luke’s Fountain of Youth mission.

Portman’s Resume: Queen Amidala/Padmé in Star Wars: Episode I – The Phantom Menace (1999), Alice in Closer (2004), Evey in V for Vendetta (2005), Nina Sayers/The Swan Queen in Black Swan (2010), Jane Foster in the MCU (2011-)

Read More at VV — Know the Cast: ‘Blitz’

Fountain of Youth Cast: Eiza González as Esme

Character Profile: Luke’s mysterious nemesis. She initially crosses paths with him in Thailand. Esme secretly works for an organization known as Protectors of the Path.

González’s Resume: Santánico Pandemonium in From Dusk Till Dawn: The Series (2014-16), Darling in Baby Driver (2017), Madame M in Fast & Furious Presents: Hobbs & Shaw (2019), Maia Simmons in Godzilla vs. Kong (2021), Auggie Salazar in 3 Body Problem (2024)

Read More at VV — Know the Cast: ‘Wolfs’

Fountain of Youth Cast: Domhnall Gleeson as Owen Carver

Character Profile: Luke’s associate. He is a businessman who funds a project to locate the Fountain of Youth. Owen claims that he is dying from liver cancer.

Gleeson’s Resume: Levin in Anna Karenina (2012), Caleb in Ex Machina (2014), Jon Burroughs in Frank (2014), General Hux in the Star Wars Movie Franchise (2015-), Sam Fortier in The Patient (2022)

Read More at VV — Know the Cast: ‘The Instigators’

The Fountain of Youth cast also includes:

• Arian Moayed as Jamal Abbas
• Laz Alonso as Patrick Murphy
• Carmen Ejogo as Deb McCall
• Stanley Tucci as The Elder
• Benjamin Chivers as Thomas
• Michael Epp as Praeger
• Steve Tran as Kasem
• Daniel De Bourg as Harold
• Perdita Weeks as Harold’s Lawyer
• Simon Shorten as Dubious Cop

Q.V. Hough (@QVHough) is Vague Visages’ founding editor.